Benadryl is a widely used medication for treating allergy symptoms, yet it can reason problems when blended with alcohol.

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Benadryl is the brand name for one antihistamine well-known as diphenhydramine. The medicine helps to minimize allergy symptoms, including rashes and coughs and irritated eyes, throat, and also nose.

While the does not influence on the liver, Benadryl is a main nervous mechanism (CNS) depressant, the same as alcohol. When it is taken through alcohol, the combined impact on the CNS can create heightened side effects. In part situations, this interaction can produce very dangerous results.


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Share top top PinterestBenadryl is a brand the antihistamines commonly used because that allergies.
Benadryl can cause side effects, including sedation and also drowsiness, which impair coordination and reaction speed.

Mixing Benadryl v alcohol deserve to intensify these side effects and also will dilute a person’s everyday functioning.

This deserve to be life-threatening if it involves certain activities, such as driving or operating heavy machinery.

2. Ns of consciousness

Some world are much more prone than others to losing consciousness once sedated. In these people, combining Benadryl and alcohol is much more likely to cause a ns of consciousness. This have the right to be harmful due to the likelihood that falls and other accidents.

3. Dehydration

Benadryl and also alcohol space both well-known to dehydrate the body. Mixing them can increase the danger of dehydration. This can reason discomfort in ~ the time and may worsen a hangover.

4. Symptom in larger adults

Aging slowly the body’s capacity to failure alcohol so that it might stay in the system of an older adult for much longer than someone younger. This slowdown boosts the time a human being will be at threat of a harmful interaction in between Benadryl and alcohol.

5. Learning and also memory impairment

Benadryl block the activity of a neurotransmitter dubbed acetylcholine. Acetylcholine is important for learning and memory, therefore blocking its activity may in the interim impair this processes.

Alcohol is also known come inhibit learning and memory temporarily. So, combining alcohol and Benadryl might again have a more noticeable impact on learning and memory.

6. Interactions v other species of medication


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Share on PinterestBenadryl may interact with cough and also cold medication.
Benadryl may connect with other species of medication, which have the right to heighten the next effects.

Taking these other species of medications with alcohol could also increase the hazard of next effects.

Examples of medicines that may connect with Benadryl include:

stomach ulcer medicinecough and also cold medicineother antihistaminesdiazepam (Valium)sedatives

7. Various other sources the alcohol

Some types of medication, consisting of cough syrup and laxatives, also contain alcohol. Lock can incorporate up to 10 percent alcohol, which may connect with Benadryl.

As a consequence, taking Benadryl v these drugs when consuming very tiny amounts that alcohol may still rise the threat of adverse side effects.

8. Sex

In general, females are an ext susceptible to alcohol-related harm. This is since their bodies generally contain less water because that alcohol to mix with, meaning that the very same amount that alcohol would be much more concentrated in a female 보다 in a male.

Mixing Benadryl through alcohol may be particularly hazardous because that females, as consuming smaller quantities of alcohol could create adverse interaction effects.

9. Misuse

As Benadryl and also alcohol both cause drowsiness and sedation, it might seem tempting to exploit this combination as a sleeping aid. However, this can additionally heighten other adverse side effects that will interfere with sleep, such as nausea and dizziness.

10. Dementia


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Share top top PinterestMore studies are forced to recognize if mix Benadryl and alcohol reasons dementia.
One study uncovered that civilization who take one anticholinergic drug per day because that at the very least 3 years have a increased risk the dementia. It should be noted that this study contained all anticholinergic drugs, not simply Benadryl.

Another examine in 2018 discovered excessive alcohol intake to be associated with a greater risk the dementia. The is possible that consuming big amounts the Benadryl and alcohol over long periods the time might be connected to an enhanced risk the dementia.

However, longitudinal study would be forced in civilization who consume high levels of Benadryl and alcohol to understand whether this has any kind of effect top top the hazard of dementia.


The risks linked with mixing Benadryl and also alcohol may not use to anyone or every situation. That is feasible that consuming little amounts that alcohol while taking Benadryl in a safe environment will reason no harm. However, the safest option is just to abstain from alcohol while acquisition Benadryl.

Under no circumstances must Benadryl and also alcohol be mixed prior to engaging in any task that compelled mental alertness, such together driving.

If who else has actually either deliberately or unintentionally combined Benadryl v alcohol, it is important to ensure they room in a safe environment, wherein they deserve to rest, if require be.

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It is ideal to consult with a physician to determine when it would be safe to consume alcohol after acquisition Benadryl, as this will depend on other factors, together as age or other courses that medication.