In our latest question and also answer, our pharmacist discusses whether or not it OK to take Zyrtec (cetirizine) with Mucinex.

You are watching: Can you take zyrtec and mucinex at the same time


Jay asked

This afternoon approximately 4pm I took a Zyrtec for allergy related symptoms, 6 hrs I took Mucinex rapid max to aid via runny nose and also sneezing. I uncovered out that both have actually antihistamine in them and also I am concerned around if I took as well much. Both have 10mg of antihistamine in them. Should I be worried?


You don"t must be worried. If you took Zyrtec and also Mucinex Fast-Max sixhours apart, the worst you are likely to suffer is included drowsiness and drymouth. Using alcohol or various other drugs through either or both of these medicationswill most likely intensify the drowsiness considerably. This may significantly impair yourcapacity to drive or usage machinery, so please use caution and be safe.

Mucinex Fast-Max is a product line in which there are multiple versions intended to treat a range of symptoms. Reviewing the ingredients of all the Fast-Max line ofassets, the nighttime varieties contain either diphenhydramine or doxylamineas an antihistamine.

A quick lesson on antihistamines. Tright here are two main households ofantihistamines, let’s contact them old-school and also new-school to make it much easier toremember.

Old-school antihistamines encompass drugs favor

Diphenhydramine (Benedryl)Doxylamine(Unisom, NyQuil)Chlorpheniramine(Chlor-Trimeton, Chlor-Tabs)

These drugs block histamine receptors in both thebrain and also the rest of the body; they likewise communicate via several various other receptorforms. This renders them good at relieving allergy symptoms, but likewise offers them afew unpleasant side effects, particularly sedation/drowsiness, dry mouth, anddry eyes.

See more: How Many Cups Does 32 Fl Oz Is How Many Cups Does 32 Ounces Equal?

New-school antihistamines incorporate drugs like:

Cetirizine (Zyrtec)Fexofenadine (Allegra)Loratadine (Claritin)

These drugs, unlike the old-college ones, are designed so that they can’tcross the barrier that protects the brain from harmful chemicals in your blood.The result is they deserve to just block histamine receptors discovered in the rest of yourbody, and also not in the brain, and also so they create allergy relief via much lessdrowsiness and various other side effects.

That sassist, this doesn’t intend they can’tmake you drowsy, and also taking them via various other antihistamines, alcohol, or drugsthat impact the main nervous mechanism (bupropion, benzodiazepines likealprazolam or clonazepam, and also others) have the right to develop substantial additive effectsthat can impair your capacity to make decisions or operate a vehicle.

Aacquire, mixingthese substances need to be avoided if possible, and also if you have to, usage caution.Thanks for your question!